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OPTIMUM E 100/100™
Full Spectrum | Physician Formula | Mixed Tocopherols & Tocotrienols
The role of Optimum E 100/100 is unique and indispensable. Its structure allows it to position itself strategically and protect the cell and other membranes. It also protects LDL and other lipids from oxidation. Research supports its benefits in anti-aging, Alzheimer's, some cancers, heart disease, and other chronic diseases. The effective levels for disease prevention and management are significantly higher than what we can get even from a well balanced diet. Only products that contain the complete vitamin E family-tocopherols plus tocotrienols-in their natural unesterified form-provide the full spectrum of benefits of vitamin E.
Vitamin E, along with other standard treatments, may also be beneficial for the following:
The word natural can, unfortunately, sometimes be misleading. In the case of vitamin E, a manufacturer can use a blend of 10% natural vitamin E and 90% synthetic vitamin E and still label the product natural vitamin E. Using synthetic vitamin E, which is 40% cheaper, a manufacturer can greatly reduce the quality of a product to reduce his manufacturing cost.
Natural vitamin E is officially recognized as having 36% greater potency than its synthetic counterpart. However, recent studies of human subjects indicate that natural vitamin E is probably twice as effective as synthetic vitamin E.
Vitamin E is a family of 8 compounds: four tocopherols and four tocotrienols. Each of the four tocopherols and tocotrienols are named after the four letters of the greek alphabet: alpha, beta, gamma, delta.
The chemical difference between the tocotrienols and the tocopherols is the double bonds on the tail. The chemical difference between the tocotrienols, like the tocopherols, is the position of the methyl groups on the chroman ring. The active component of the tocopherols and tocotrienols is the hydroxyl group on the chroman ring.
The eight members of the vitamin E family have some functions that are similar to the others and other functions that are completely different. These members also are present in different areas of the body in various amounts. For example, there is more gamma-tocopherol than alpha-tocopherol in the skin.
Mention vitamin E and many people in the food and nutrition business will still of think alpha-tocopherol. First, it is present in the human body in the highest level of all members. Second, it is by far the most effective of the eight in the classical vitamin E assay for what we thought was its main function ø to support reproduction.
It is only recently that scientists have been reminded that there is more to vitamin E, seven more members that have long been ignored. Strong scientific research indicates that the long ignored members have important functions, some of which are different from those of alpha-tocopherol.
Everyone has heard of international units (IU) which were meant to be the vitamin E currency. Unfortunately, this basis was created when alpha-tocopherol was believed to be the only compound in vitamin E. The IU was based on alpha-tocopherol acetate.
For Your Information:
1 mg alpha-tocopherol acetate = 1.0 IU alpha-tocopherol acetate
1 mg alpha-tocopherol = 1.49 IU alpha tocopherol
* Thus, they must be measured in milligrams. To make matters more confusing, the Food and Nutrition Board of the National Research Council scrapped the IU and replaced it with the alpha-tocopherol equivalent (alpha-TE) in order to account for all 8 members of the vitamin E family, but only in foods NOT in supplements. One alpha-TE is one milligram of natural d-alpha-tocopherol. However, the IU is still the industry standard in the United States and many other countries and unfortunately, the alpha-TE on the label does not tell us much more than the IU.
According to the National Academy of Science the Recommended Daily Intake (RDI) for vitamin E is 15 milligrams which is equivalent to 22 International Units (IU) of natural alpha-tocopherol or 33 IUs of the synthetic form. Of course, we must understand that the RDI is a measure of vitamin E used to prevent deficiency; NOT the amount that is necessary to prevent disease and thus promote wellness. The RDA (Recommended Daily Allowance) is still used on food labels, and is 30 IU of alpha- tocopherol.
Vitamin E can be found in vegetable oils, grains, nuts and green leafy vegetables. Corn and soybean oil have proportionally more gamma-tocopherol than other oils. Can you get you 400 IU from food only, instead of supplements? Yes...if you can eat 1000 almonds (658g of fat) or 120 cups of broccoli!
Optimum E is derived from GMO-free soybean oil (does not contain soy protein) and rice bran oil which are the best sources for natural tocopherols and tocotrienols. All of the negative elements related to soy have been safely removed leaving only the valuable vitamin E elements. Research indicates the body's preference for natural vitamin E over synthetic vitamin E. Natural vitamin E has roughly twice the availability of synthetic vitamin E.
Vitamin E is extremely safe. But it is important to talk with your physician before beginning any new supplements, especially if you are taking prescription medications. We recommend specifically that you speak with a physician if you have problems with blood clotting or you are taking blood thinners.
The safe Upper Intake Level (UL) for vitamin E has been set at 1000 IU. However, alandmark study of Alzheimer's and vitamin E used 2000 IU of vitamin E for two years without significant complications as compared to placebo. Another study used doses at 3200 IU/day, so even at higher doses vitamin E has been found to be relatively safe.
The October 16 edition of the Wall Street Journal focused on the vitamin E family and the role of gamma-tocopherol. It stated that: Most people purchase alpha-tocopherol as their vitamin E and do not purchase products that contain the whole family of vitamin E (eight different compounds- four tocopherols and 4 tocotrienols). Many scientists now believe that a less commonly available type -- one called gamma-tocopherol -- is far more beneficial. The focus on gamma-tocopherol is very welcome because of its potential role in reducing the risk of prostate cancer. In addition gamma-tocopherol fights the nitrogen free radicals which are culprits in neurodegenerative diseases such as Alzheimer's and Parkinson's. It is important to keep in mind, however, that the other tocopherols and the tocotrienols may have important roles.
Gamma-tocopherol, not alpha-tocopherol, is the effective form that fights against nitrogen free radicals. These radicals are major culprits in arthritis, multiple sclerosis (MS) and diseases of the brain (such as Alzheimer's). A metabolic product of gamma-tocopherol appears to help regulate the amount of fluid and electrolytes that pass through the kidney and end up in urine. This means that it could play a major role in blood pressure control, congestive heart failure, and cirrhosis of the liver. The corresponding metabolite of alpha-tocopherol is not active in this regard.
US and Swedish researchers have reported that gamma-tocopherol was more potent than alpha-tocopherol in several major effects:
Our Optimum E supplies natural tocopherols plus tocotrienols formulated using the latest scientific and clinical research to provide quantities that will help to promote wellness and prevent disease. Our Optimum E provides the whole vitamin E family of tocopherols plus tocotrienols in their natural unesterified form as found in our food. Our Optimum E is particularly rich in the natural d-gamma-tocopherol and tocotrienols. These overlooked members of the vitamin E family promote cardiovascular health and skin health, help prevent some cancers, and other diseases. While some of the functions of the non-aplha tocopherols and tocotrienols are similar to those of alpha-tocopherol, others are unique and cannot be performed by alpha-tocopherol. For a complete discussion of the science please read The Vitamin E Factor book by Andreas Papas (HarperCollins, 1999).
Most vitamin E supplements, however, contain only alpha-tocopherol and usually the synthetic esterified form dl-alpha-tocopheryl acetate. Others which claim to supply tocopherols, contain alpha-tocopherol but extremely small amounts of the other tocopherols and tocotrienols. They may "claim" to have the whole family of vitamin E, BUT read the label carefully to be sure.
Net Content: 120 vegetarian Licaps®
Serving Size: 1 V-Cap
Servings Per Container: 120
|Vitamin E (as natural d-alpha tocopherol and mixed tocopherols) 333% of Daily Value||100 IU|
|Mixed tocopherols 70% (consisting of D-alpha, D-beta, D-gamma, D-delta)||50 mg|
|Rice Bran Tocotrienols & Tocopherols 30% (consisting of D-alpha, D-beta, D-gamma, D-delta)||50 mg|
|Other Ingredients: Lecithin (GMO-free) and vegetable cellulose capsules|
As a dietary supplement, take 1 capsule twice daily. For maximum benefit take 2 capsules twice daily.
Caution: If you are pregnant or nursing, DO NOT take this product. Consult your healthcare practitioner if you are taking blood thinning medication. Individuals who are vitamin K deficient should not take alpha-tocopherol supplements without close medical supervision because of the increased risk of hemorrhage.
Encapsulated in special liquid vegetable capsules with a nitrogen bubble to protect the vitamin E and tocotrienols oil from oxidation.
Manufactured in an FDA Registered Facility using Good Manufacturing Practices (GMPs).